There is a thread called "leaking side windows," and some answers are there.
I ran a company making seals which are extruded nitrial and UV will take its toll quickly if no maintenance is carried out, by that I mean use silicone, or Vaseline which I have used for 40 years on my hatches with great results.
Over tightening is a probelem as well because it will give the nitrial a "memory" so just be carfull when closing the hatches and windows, a bit on TLC will more than pay for its self.
Odysseus